Contraindicated. CYP3A4 is responsible for the development and elimination of cariprazine's Lively metabolites. The influence of CYP3A4 inducers on cariprazine exposure has not been evaluated plus the Web influence is unclear.
pentobarbital will minimize the extent or effect of fosaprepitant by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
pentobarbital will reduce the extent or effect of conivaptan by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
pentobarbital will decrease the level or influence of cortisone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
pentobarbital will reduce the extent or influence of voriconazole by influencing hepatic enzyme CYP2C9/ten metabolism. Minimal/Importance Mysterious.
pentobarbital will decrease the level or outcome of triazolam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
pentobarbital will reduce the extent or effect of eplerenone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Unknown.
Treatment often demands intubation, hemodynamic support with vasopressors, and retaining physique temperature with warmers, normally within an intensive treatment unit (ICU) placing. In mild or early scenarios of toxicity, activated charcoal and alkaline diuresis are included but demonstrate minimal Advantages. Generally Get in touch with poison Regulate if poisoning or overdose is suspected.
pentobarbital will reduce the extent or influence of vinorelbine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Significance Unfamiliar.
pentobarbital will minimize the level or influence of zaleplon by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Not known.
pentobarbital will minimize the level or outcome of lopinavir by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
pentobarbital will lower the extent or outcome of fentanyl intranasal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Check Intently. Coadministration of fentanyl with CYP3A4 inducers could lead on to some decrease in fentanyl plasma concentrations, lack of efficacy or, perhaps, growth of the withdrawal syndrome inside of more info a patient that has designed physical dependence to fentanyl.
pentobarbital will lower the extent or result of vinblastine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Importance Unfamiliar.
pentobarbital will lessen the level or influence of dutasteride by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Unknown.